@ccimhealth we discuss important features about your immune system and how to make your #immune system more effective at protecting you from #viral infection including covid19. There's evidence that people who never were exposed to the #covid19 virus can still yet have an inflammatory response to it.

As data start to accumulate on the detection and characterization of #SARSCoV2 T cell responses in humans, a surprising finding has been reported: lymphocytes from 20–50% of unexposed donors display significant reactivity to #SARS-CoV-2 antigen peptide pools.

In a study by Grifoni et al.1, reactivity was detected in 50% of donor blood samples obtained in the #USA between 2015 and 2018, before SARS-CoV-2 appeared in the human population. T cell reactivity was highest against proteins other than the coronavirus spike protein, but T cell reactivity was also detected against spike. The SARS-CoV-2 T cell reactivity was mostly associated with CD4+ T cells, with a smaller contribution by CD8+ T cells.


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